Descripción del Proyecto
This proposal aims to promote a transnational network for drug repurposing.Due to the high failure rates, costs and slowness of the discovery and development process of new drugs, the use of drugs to treat diseases different from those that were originally defined is an increasingly important strategy. In addition, once the drug safety profile is already defined, both based on pre-commercialization studies involving clinical trials, as well as post-commercialization studies with real life data, the drug repurposing means savings of many years and millions of euros in R&D, with benefits for the society, the pharmaceutical industry and especially for patients.
As a case study, drug repurposing for the treatment of cancer, by tackling an important component of the Hippo signaling pathway (HP), involved in controlling cell grow and organ size will be implemented. Other case studies on drug repurposing should be generated from the project partners and be implemented.